Assigning Absolute Configuration.
The files listed below each contain one chiral molecule which can be manipulated using the Chemscape Chime plugin. In each of these exercises, you will be required to assign priorities around the chiral center(s), rotate the molecule into an appropriate conformation, and determine if the absolute configuration of the molecule is R or S. If you wish to do the molecules in sequence, begin with the Sample Problem and continue through the set. If you wish to go directly to a specific problem, simply click on the link below.
Sample Problem
#1: Tartaric acid
#2: Limonene
#3: 4-Methyl-3-nitrohexane
#4: Methyloxirane
#5: Tartaric acid
#6: 1-Iodo-2-methylcyclohexane
#7: 2-Bromo-3-isopropoxy-4-methylpentane
#8: 2,6-Diiodo-4-isopropylheptane
#9: 3-Cyclobutyl-1-cyclopropyl-4-methylpentane
#10: 3-Propyl-1,6-heptadiyne
#11: 3-Bromo-2-butanol
#12: 4-Methyl-3-nitrohexane
#13: 3-Ethyl-4-cyclopentylhexane
#14: 2-Butyl p-toluenesulphonate
#15: 3-Ethoxy-2-fluorohexane
#16: 1,2,4-Triethylcyclopentane
#17: 1,2-Dibromo-4-tert-butylcyclohexane
#18: Ascorbic Acid
#19: Enanthotoxin
#20: 4-Ethyl-2-isopropylbicyclo[4.1.0]heptane