Reactions of
Carboxylic Acid Derivatives

For each of the reactions on the left, predict the major organic product. Pay particular attention to the regiochemistry and stereochemistry of the reaction.

Click the mouse on the reactant molecule to view the answer;

click on the reagent to briefly review the reaction.

The reaction of an acid halide with diarylcopperlithium reagent will convert the acid halide into the corresponding ketone.

The reduction of a nitrile with LiAlH4 results in the addition of two equivalents of hydride to the nitrile carbon, forming the primary amine.

The reaction of a carboxylic ester with a Grignard reagent will result in the addition of two equivalents of the Grignard, converting the ester into the corresponding tertiary alcohol.. 





















 


The reaction of a nitrile with a Grignard reagent will result in the addition of one equivalents of the Grignard, converting the nitrile into the corresponding ketone..































The reaction of an acid halide with diarylcopperlithium reagent will convert the acid halide into the corresponding ketone.






























The reduction of a nitrile with LiAlH4 results in the addition of two equivalents of hydride to the nitrile carbon, forming the primary amine.






























The reaction of a carboxylic ester with a Grignard reagent will result in the addition of two equivalents of the Grignard, converting the ester into the corresponding tertiary alcohol..
































The reaction of a nitrile with a Grignard reagent will result in the addition of one equivalents of the Grignard, converting the nitrile into the corresponding ketone..