Reactions of Grignard Reagents with Carbonyls
For each of the reactions on the left, predict the major organic product.Click the mouse on the reactant molecules to view the answer;
click on the arrow for a brief overview of the reaction.
The addition of the Grignard reagent to a ketone converts the carbonyl group into a tertiary alcohol. The atoms arising from the carbonyl compound and the Grignard reagent are shown below in blue and red, respectively.
The addition of the Grignard reagent to an ester converts the carbonyl group into a tertiary alcohol. The atoms arising from the carbonyl compound and the Grignard reagent are shown below in blue and red, respectively. Recall that the intermediate in this reaction (a ketone) adds the second mole of Grignard reagent.
The addition of the Grignard reagent to a ketone converts the carbonyl group into a tertiary alcohol. The atoms arising from the carbonyl compound and the Grignard reagent are shown below in blue and red, respectively.
The addition of the Grignard reagent to a ketone converts the carbonyl group into a tertiary alcohol.
The addition of the Grignard reagent to an ester converts the carbonyl group into a tertiary alcohol.
The addition of the Grignard reagent to a ketone converts the carbonyl group into a tertiary alcohol.